Healing by primary intention is a threefold process, consisting of an initial phase in which red and white blood cells bind the wound; epithelialization and fibroplasia, and a maturation phase involving collagen synthesis. The appearance of the wound reflects its maturation. Skillful wound management is based on biologic principles. Time factors in wound closure, the effects of anesthetic techniques, debridement, the selection of sutures and the methods of suturing have profound effects on the outcome.
