Mercier C, Robert M, Lacombe A, Martin L, Gold F, Laugier J
Arch Fr Pediatr. 1984 Aug-Sep;41(7):459-65.
The experience of the authors concerns 100 neonates treated for esophageal atresia between 1968 and 1980. A retrospective study of the sequelae observed in 73 survivors (age 3 to 15 years) found 26 cases of gastroesophageal reflux. This study demonstrates a high incidence of reflux in children who initially presented with a fistula and long gap esophageal atresia. It also shows that chronic respiratory disorders are more frequent in these patients and that esophagitis is the principal factor leading to stricture of the anastomosis stubborn to dilatation. In 14 patients, the severity of the clinical and endoscopic symptoms justified a surgical antireflux procedure, the only guarantee of clinical and radiologic recovery, with long term confirmation in 9 patients.
作者的经验涉及1968年至1980年间接受食管闭锁治疗的100例新生儿。对73名幸存者(年龄3至15岁)观察到的后遗症进行的回顾性研究发现26例胃食管反流。这项研究表明,最初表现为瘘管和长间隙食管闭锁的儿童中反流发生率很高。它还表明,这些患者中慢性呼吸系统疾病更为常见,食管炎是导致吻合口狭窄难以扩张的主要因素。在14名患者中,临床和内镜症状的严重程度证明了手术抗反流手术的合理性,这是临床和放射学恢复的唯一保证,9名患者得到了长期证实。