Sentou Y, Cohen G, Nussaume O
J Mal Vasc. 1985;10(2):153-7.
Technical progress in echotomography has made it possible to identify a number of structures within the atheromatous lesion itself. Such echotomographic data were compared with peroperative findings and histology of the endarterectomy specimen in the context of carotid pathology. Appearances were differentiated in terms of the density and homogeneity of the echos obtained. Heterogeneous and relatively undense lesion corresponded in the majority of cases with moveable intraluminal matter or intraplaque hematomas. False negatives were due in one case to technical impossibility (calcifications) and in one case to multiple ulcerations. Regular and homogeneous appearances corresponded to fibrous plaques, rich in collagen and free of potential emboligenic material. Preoperatively, echotomography may be used to assess the histological characteristics of a plaque with a high degree of sensitivity and good specificity. This new approach may help in the choice of treatment and will improve knowledge of the natural history of carotid lesions necessary for the study of preventive treatment, in particular in asymptomatic patients.
超声断层扫描技术的进步使得识别动脉粥样硬化病变本身内的一些结构成为可能。在颈动脉病变的背景下，将此类超声断层扫描数据与动脉内膜切除术标本的术中发现和组织学进行了比较。根据所获得回声的密度和均匀性对表现进行了区分。在大多数情况下，异质性和相对低密度的病变与腔内可移动物质或斑块内血肿相对应。假阴性在一例中是由于技术上的不可能（钙化），在另一例中是由于多处溃疡。规则且均匀的表现对应于富含胶原蛋白且无潜在栓塞物质的纤维斑块。术前，超声断层扫描可用于以高度的敏感性和良好的特异性评估斑块的组织学特征。这种新方法可能有助于治疗方案的选择，并将增进对颈动脉病变自然史的了解，这对于预防性治疗的研究，特别是对无症状患者而言是必要的。
