Smith G R
Isr J Med Sci. 1984 Oct;20(10):965-9.
Fresh isolates of the small colony (SC) type of Mycoplasma mycoides subsp. mycoides readily produced mycoplasmaemia in mice inoculated i.p. The mycoplasmaemic capability of large colony (LC) strains was much less by comparison. Cross-immunization and -hyperimmunization tests in mice were made by injecting vaccines i.v., challenging i.p., and assessing the results on the presence or absence of mycoplasmaemia at daily intervals thereafter, as demonstrated by tail-blood culture in a selective medium. In terms of mouse-protective antigens, the SC and LC types were related but not identical. SC strains, unlike LC strains, were homogeneous. The SC and LC types differed from M. mycoides subsp. capri but were nonetheless related to it, the former less closely than the latter. Cross-immunization by M. mycoides subsp. mycoides (SC and LC types) against M. mycoides subsp. capri was often, but not always, unidirectional.
丝状支原体山羊亚种小菌落（SC）型的新鲜分离株经腹腔接种小鼠后很容易引起支原体血症。相比之下，大菌落（LC）菌株的致支原体血症能力要低得多。通过静脉注射疫苗、腹腔攻毒，并通过在选择性培养基中进行尾血培养来每日间隔评估有无支原体血症的结果，对小鼠进行交叉免疫和超免疫试验。就小鼠保护性抗原而言，SC型和LC型相关但不相同。与LC菌株不同，SC菌株是同质的。SC型和LC型与丝状支原体山羊亚种不同，但仍与之相关，前者的相关性低于后者。丝状支原体丝状亚种（SC型和LC型）对丝状支原体山羊亚种的交叉免疫通常（但并非总是）是单向的。
