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钾、镁与细胞膜。现状及新发现综述

Potassium, magnesium and membranes. Review of present status and new findings.

作者信息

Bara M, Guiet-Bara A

出版信息

Magnesium. 1984;3(4-6):215-25.

PMID:6399343
Abstract

The interactions between magnesium, potassium and various membranes were examined. The different membranes chosen were: artificial, erythrocyte, cardiac, muscular, nervous, gallbladder, urinary bladder, mitochondrial and human amniotic. In general, Mg++ and K+ act on the cellular adhesion and on the stability of the membrane by forming bonds between the charges of the lipids and the proteins. Mg++ acts on the passive K+ transfer either by activation or inhibition. In addition, Mg++ acts on the K+ active transfer: the presence of Mg++ is essential to maintain the activity of the membrane (Na+K) adenosine triphosphatase (ATPase).

摘要

研究了镁、钾与各种膜之间的相互作用。所选用的不同膜包括:人工膜、红细胞膜、心肌膜、肌肉膜、神经膜、胆囊膜、膀胱膜、线粒体膜和人羊膜。一般来说,镁离子(Mg++)和钾离子(K+)通过在脂质和蛋白质的电荷之间形成键来作用于细胞黏附及膜的稳定性。镁离子对钾离子的被动转运起激活或抑制作用。此外,镁离子作用于钾离子的主动转运:镁离子的存在对于维持膜(钠钾)三磷酸腺苷酶(ATP酶)的活性至关重要。

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