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磷脂在跨膜钾离子运输中的直接参与。

Direct participation of phospholipids in transmembrane K(+)-transport.

作者信息

Medvedev B I, Yurkov I S

机构信息

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region.

出版信息

Membr Cell Biol. 1997;10(5):573-81.

PMID:9225261
Abstract

The correlation between the characteristics of K(+)-transport across the mitochondrial and bilayer lipid membranes formed form mitochondrial lipids has been demonstrated. It has been shown that different modes of K(+)-efflux activation in mitochondria result in the appearance of K(+)-transporting phospholipid forms. The experiments described in this work suggest that current fluctuations similar to those observed for biological channels can be registered in unmodified bilayer lipid membranes containing no protein components.

摘要

已经证实了线粒体中钾离子转运特性与由线粒体脂质形成的双层脂质膜之间的相关性。研究表明,线粒体中钾离子外流激活的不同模式会导致钾离子转运磷脂形式的出现。这项工作中描述的实验表明,在不含蛋白质成分的未修饰双层脂质膜中可以记录到与生物通道中观察到的类似的电流波动。

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