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与马立克氏病肿瘤相关表面抗原(MATSA)反应的单克隆抗体的分离

Isolation of monoclonal antibodies reactive with Marek's disease tumor-associated surface antigen (MATSA).

作者信息

Ikuta K, Ueda S, Kato S, Ono K, Osafune S, Yoshida I, Konobe T, Naito I, Naito M, Hirai K

出版信息

Biken J. 1984 Dec;27(4):183-8.

PMID:6399439
Abstract

Two hybridoma clones producing monoclonal antibodies were obtained from mice immunized with the Marek's disease (MD)-lymphoblastoid cell line MSB1. These monoclonal antibodies reacted with the surface of MD-lymphoblastoid cell lines at higher titers than with avian lymphoid leukosis cell lines or with normal chicken thymus, bursa or peripheral blood lymphocytes. The serological specificity of these monoclonal antibodies seemed to correspond with that of rabbit antiserum reactive with MD tumor-associated surface antigen (MATSA).

摘要

从用马立克氏病(MD)-淋巴母细胞系MSB1免疫的小鼠中获得了两个产生单克隆抗体的杂交瘤克隆。这些单克隆抗体与MD-淋巴母细胞系表面反应的效价比与禽淋巴细胞白血病细胞系或正常鸡胸腺、法氏囊或外周血淋巴细胞反应的效价更高。这些单克隆抗体的血清学特异性似乎与与MD肿瘤相关表面抗原(MATSA)反应的兔抗血清的特异性一致。

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Isolation of monoclonal antibodies reactive with Marek's disease tumor-associated surface antigen (MATSA).与马立克氏病肿瘤相关表面抗原(MATSA)反应的单克隆抗体的分离
Biken J. 1984 Dec;27(4):183-8.
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A monoclonal antibody reactive with Marek's disease tumor-associated surface antigen.一种与马立克氏病肿瘤相关表面抗原发生反应的单克隆抗体。
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