麻风分枝杆菌悬液对麻风病患者多形核中性粒细胞针对白色念珠菌和伪热带念珠菌功能的体外影响。
In vitro effect of Mycobacterium leprae suspensions on the polymorphonuclear neutrophils function of hanseniasis patients to Candida albicans and Candida pseudotropicalis.
作者信息
Fliess E L, Franceschini G, Ortiz M C
机构信息
Laboratory Department, National Hospital Baldomero Sommer, General Rodríguez, Argentina.
出版信息
Hansenol Int. 1984 Jun-Dec;9(1-2):3-9.
The in vitro effect of Mycobacterium leprae suspensions on the PMN ability to phagocytizing and killing Candida albicans and Candida pseudotropicalis was studied in forty-five patients of Hansen's disease and in fifteen healthy controls. Our results show no significative differences between the different studied groups, both for the phagocytosis and for the lysis of yeasts. There was no significant changes in the mean values of these functions after previous or simultaneously incubation with Mycobacterium leprae suspensions. Those observations confirmed that there are not alterations in the enzymatic battery of PMN in Hansen's disease patients and that the Mycobacterium leprae presence does not exert stimulating effect on this in vitro model.
在45例麻风病患者和15名健康对照者中，研究了麻风分枝杆菌悬液对中性粒细胞吞噬和杀灭白色念珠菌及伪热带念珠菌能力的体外影响。我们的结果显示，在不同研究组之间，无论是酵母的吞噬作用还是裂解作用，均无显著差异。在用麻风分枝杆菌悬液预先孵育或同时孵育后，这些功能的平均值没有显著变化。这些观察结果证实，麻风病患者中性粒细胞的酶系统没有改变，并且麻风分枝杆菌的存在对该体外模型没有刺激作用。
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