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Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.

作者信息

Rebecchi M J, Kolesnick R N, Gershengorn M C

出版信息

J Biol Chem. 1983 Jan 10;258(1):227-34.

PMID:6401292
Abstract
摘要

相似文献

1
Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.促甲状腺激素释放激素可刺激大鼠促乳腺垂体细胞中磷脂酰肌醇的快速丢失及其向1,2 - 二酰甘油和磷脂酸的转化。这与钙动员和催乳素分泌有关。
J Biol Chem. 1983 Jan 10;258(1):227-34.
2
Effects of thyrotropin-releasing hormone on phosphoinositides and cytoplasmic free calcium in thyrotropic pituitary cells.促甲状腺激素释放激素对促甲状腺垂体细胞中磷酸肌醇和细胞质游离钙的影响。
Endocrinology. 1986 Jan;118(1):163-9. doi: 10.1210/endo-118-1-163.
3
Pertussis toxin blocks the inhibitory effects of somatostatin on cAMP-dependent vasoactive intestinal peptide and cAMP-independent thyrotropin releasing hormone-stimulated prolactin secretion of GH3 cells.百日咳毒素可阻断生长抑素对环磷酸腺苷（cAMP）依赖性血管活性肠肽以及对环磷酸腺苷非依赖性促甲状腺激素释放激素刺激GH3细胞分泌催乳素的抑制作用。
J Biol Chem. 1986 Feb 25;261(6):2684-9.
4
Thyrotropin-releasing hormone stimulates rapid breakdown of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate in GH3 pituitary tumor cells.促甲状腺激素释放激素刺激GH3垂体瘤细胞中磷脂酰肌醇4,5-二磷酸和磷脂酰肌醇4-磷酸的快速分解。
Mol Pharmacol. 1984 Mar;25(2):193-200.
5
Inositol trisphosphate mediates thyrotropin-releasing hormone mobilization of nonmitochondrial calcium in rat mammotropic pituitary cells.肌醇三磷酸介导促甲状腺激素释放激素对大鼠催乳素分泌垂体细胞中非线粒体钙的动员。
J Biol Chem. 1984 Sep 10;259(17):10675-81.
6
Thyrotropin (TSH)-releasing hormone decreases phosphatidylinositol and increases unesterified arachidonic acid in thyrotropic cells: possible early events in stimulation of TSH secretion.促甲状腺激素释放激素可降低促甲状腺细胞中的磷脂酰肌醇水平，并增加未酯化的花生四烯酸：这可能是刺激促甲状腺激素分泌的早期事件。
Endocrinology. 1984 Feb;114(2):671-6. doi: 10.1210/endo-114-2-671.
7
Inositol lipid metabolism and signal transduction in clonal pituitary cells.
J Exp Biol. 1986 Sep;124:337-58. doi: 10.1242/jeb.124.1.337.
8
Evidence for the role of calcium and diacylglycerol as dual second messengers in thyrotropin-releasing hormone action: involvement of diacylglycerol.
Endocrinology. 1984 Oct;115(4):1517-26. doi: 10.1210/endo-115-4-1517.
9
Calcium influx is not required for thyrotropin-releasing hormone stimulation of prolactin release from GH3 cells.促甲状腺激素释放激素刺激GH3细胞释放催乳素并不需要钙离子内流。
Cell Calcium. 1983 Apr;4(2):117-24. doi: 10.1016/0143-4160(83)90040-4.
10
Molecular species of phosphatidylinositol, phosphatidic acid and diacylglycerol in a phytohemagglutinin-stimulated T-cell leukemia line.植物血凝素刺激的T细胞白血病细胞系中磷脂酰肌醇、磷脂酸和二酰基甘油的分子种类
Biochim Biophys Acta. 1985 Feb 8;833(2):316-22.

引用本文的文献

1
TRH is a tonic secretagogue in growth hormone secreting but not in nonfunctioning pituitary tumors.促甲状腺激素释放激素（TRH）对生长激素分泌性垂体瘤是一种兴奋性促分泌素，但对无功能垂体瘤则不然。
J Endocrinol Invest. 1999 Feb;22(2):104-8. doi: 10.1007/BF03350888.
2
Plasma GH responses to GHRH, arginine, L-dopa, pyridostigmine, sequential administrations of GHRH and combined administration of PD and GHRH in Turner's syndrome.特纳综合征患者血浆生长激素对生长激素释放激素、精氨酸、左旋多巴、吡啶斯的明、生长激素释放激素的序贯给药以及吡啶斯的明与生长激素释放激素联合给药的反应。
J Endocrinol Invest. 1998 Feb;21(2):72-7. doi: 10.1007/BF03350318.
3
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
电离辐射作用于细胞膜以生成神经酰胺并引发细胞凋亡。
J Exp Med. 1994 Aug 1;180(2):525-35. doi: 10.1084/jem.180.2.525.
4
A transient increase in diacylglycerols is associated with the action of vasopressin on hepatocytes.二酰基甘油的短暂增加与血管加压素对肝细胞的作用有关。
Biochem J. 1984 Sep 1;222(2):535-40. doi: 10.1042/bj2220535.
5
The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Enhancement of stimulated 1,2-diacylglycerol formation.锂与促甲状腺激素释放激素刺激的GH3垂体瘤细胞脂质代谢的相互作用。刺激的1,2 - 二酰甘油形成增强。
Biochem J. 1984 Nov 15;224(1):129-36. doi: 10.1042/bj2240129.
6
Solubilization and characterization of thyrotropin-releasing hormone receptors from rat brain.大鼠脑促甲状腺激素释放激素受体的溶解与特性分析
Proc Natl Acad Sci U S A. 1984 Jul;81(13):4227-31. doi: 10.1073/pnas.81.13.4227.
7
Thyroliberin stimulates rapid hydrolysis of phosphatidylinositol 4,5-bisphosphate by a phosphodiesterase in rat mammotropic pituitary cells. Evidence for an early Ca2+-independent action.促甲状腺素释放激素通过大鼠促乳腺垂体细胞中的磷酸二酯酶刺激磷脂酰肌醇4,5-二磷酸的快速水解。早期不依赖钙离子作用的证据。
Biochem J. 1983 Nov 15;216(2):287-94. doi: 10.1042/bj2160287.
8
Inositol trisphosphate and diacylglycerol as second messengers.肌醇三磷酸和二酰甘油作为第二信使。
Biochem J. 1984 Jun 1;220(2):345-60. doi: 10.1042/bj2200345.
9
Characterization of pituitary calcium-activated, phospholipid-dependent protein kinase: redistribution by gonadotropin-releasing hormone.垂体钙激活磷脂依赖性蛋白激酶的特性：促性腺激素释放激素引起的再分布
Proc Natl Acad Sci U S A. 1985 Dec;82(23):8203-7. doi: 10.1073/pnas.82.23.8203.
10
Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation.从GH3细胞中耗尽花生四烯酸。对肌醇磷脂周转和细胞活化的影响。
Biochem J. 1987 Sep 15;246(3):669-79. doi: 10.1042/bj2460669.