Chaudhry R P, Waters B G
J Clin Psychiatry. 1983 Jan;44(1):30-1.
A case is described of a 22-year-old woman with bipolar affective disorder who developed severe neurotoxic symptoms when treated with a combined regimen of lithium carbonate and carbamazepine in therapeutic doses. An open A-B-C-B trial of the two medications separately and concurrently implicated a synergistic interaction between the two.
本文描述了一名22岁双相情感障碍女性患者，在接受治疗剂量的碳酸锂和卡马西平联合治疗时出现严重神经毒性症状。一项针对这两种药物分别及联合使用的开放性A-B-C-B试验表明二者之间存在协同相互作用。
