Grigor'eva O N, Gusel' V A, Kozhevnikova N Iu, Vlasov G P
Biull Eksp Biol Med. 1983 Feb;95(2):36-8.
Experiments on rats with electrochemotrodes implanted in the left and right hippocamp have shown that in epileptogenic foci created by microinjections of met-enkephalin or D-ala-2-met-enkephalin into the hippocamp, acetylcholinesterase activity (AChE) was diminished. It is assumed that reduction in AChE activity is an adaptive mechanism by which the excitability of hippocampal inhibitory basket cells, which are sensitive to acetylcholine, is increased.
对在左右海马体植入电化学电极的大鼠进行的实验表明，在通过向海马体微量注射甲硫氨酸脑啡肽或D-丙氨酸-2-甲硫氨酸脑啡肽所形成的致痫灶中，乙酰胆碱酯酶（AChE）活性降低。据推测，AChE活性降低是一种适应性机制，通过该机制，对乙酰胆碱敏感的海马体抑制性篮状细胞的兴奋性会增加。
