Gusel' V A, Vol'f N L, Ferdman L A
Biull Eksp Biol Med. 1985 Jan;99(1):27-9.
Experiments were performed on rabbits with electrochemotrodes implanted into the left and right dorsal hippocamp. The evidence was obtained for the first time as to the marked inhibitory effect of acupuncture on epileptogenic foci created by penicillin microinjections into the hippocamp. The most effective was stimulation of the Min-Men point. The antiepileptic effect was potentiated on combined stimulation of the Min-Men and Yao-Yan-Guan points. The efficacy of the procedure was significantly decreased on stimulation of the points of another acupunctural canal. The epileptiform activity was potentiated by affecting the knowingly inactive points. The antiepileptic effect of acupuncture was significantly reduced with an increase in the number of acupunctures. This might be connected with the development of tolerance to enkephalins by which the effect of acupuncture is most likely mediated.
对将电化学电极植入左右背侧海马体的兔子进行了实验。首次获得证据表明，针灸对通过向海马体微量注射青霉素所产生的致痫灶具有显著的抑制作用。最有效的是刺激“命门”穴。联合刺激“命门”穴和“腰阳关”穴可增强抗癫痫作用。刺激另一条针灸经络的穴位时，该操作的效果显著降低。刺激明知不活跃的穴位会增强癫痫样活动。随着针刺次数的增加，针灸的抗癫痫作用显著降低。这可能与对脑啡肽耐受性的发展有关，针灸的作用很可能是通过脑啡肽介导的。
