Mitchell H K, Roach J, Petersen N S
Dev Biol. 1983 Feb;95(2):387-98. doi: 10.1016/0012-1606(83)90040-4.
We describe in this paper details of morphogenesis of wing hairs in Drosophila pupae. The ultimate objective is to relate specific protein components used in hair construction to specific components produced in the rapidly changing patterns of gene expression that are characteristic for the period of hair differentiation in wing cells (H. K. Mitchell and N. S. Petersen, 1981, Dev. Biol. 85, 233-242). Hair extrusion to essentially full size occurs quite suddenly at about 34 hr (postpupariation) and this is followed by deposition of a double-layer of cuticulin during the next 4 to 5 hr. Extreme changes in shape of cells and hairs, probably related to actin synthesis, then occur for the next 5 to 6 hr. Deposition of fibers within the hairs and on hair pedestals follows. Formation of cuticle on the cell surface begins and continues until some time in the 60-hr range. It appears that cuticle is formed only on the cell surface and not in hairs or on the top of hair pedestals. The protein synthesis patterns associated with these events are described.
我们在本文中描述了果蝇蛹翅毛形态发生的细节。最终目标是将用于毛构建的特定蛋白质成分与在翅细胞毛分化时期特有的快速变化的基因表达模式中产生的特定成分联系起来（H. K. 米切尔和N. S. 彼得森，1981年，《发育生物学》85卷，233 - 242页）。在大约34小时（化蛹后），毛的挤出基本达到全长，这一过程相当突然，随后在接下来的4到5小时内会沉积双层表皮素。在接下来的5到6小时内，细胞和毛的形状会发生剧烈变化，这可能与肌动蛋白合成有关。随后，毛内和毛基座上会沉积纤维。细胞表面角质层的形成开始并持续到60小时左右的某个时间。似乎角质层仅在细胞表面形成，而不在毛内或毛基座顶部形成。本文描述了与这些事件相关的蛋白质合成模式。
