计算机断层扫描在韦斯特综合征研究中的应用

Computerized tomography in the study of West's syndrome.

作者信息

Gastaut H, Gastaut J L, Régis H, Bernard R, Pinsard N, Saint-Jean M, Roger J, Dravet C

出版信息

Dev Med Child Neurol. 1978 Feb;20(1):21-7. doi: 10.1111/j.1469-8749.1978.tb15178.x.

DOI:10.1111/j.1469-8749.1978.tb15178.x

Abstract

37 children presenting with West's syndrome were studied by computerized tomography scanning. An abnormality consisting of diffuse cerebral atrophy, predominating in the fronto-temporal region, was demonstrated in 30 cases. The abnormality was sometimes associated with calcification (tuberous sclerosis) or malformation (agenesis of the corpus callosum). The aetiology of the atrophy and its relationship to clinical and electroencephalographic signs is discussed. Computerized tomography scanning is recommended for children with West's syndrome in order to distinguish between primary and secondary cases, and for greater prognostic accuracy.

摘要

对37例患有韦斯特综合征的儿童进行了计算机断层扫描研究。30例显示出一种以额颞叶区域为主的弥漫性脑萎缩异常。这种异常有时与钙化（结节性硬化症）或畸形（胼胝体发育不全）有关。讨论了萎缩的病因及其与临床和脑电图征象的关系。建议对患有韦斯特综合征的儿童进行计算机断层扫描，以便区分原发性和继发性病例，并提高预后准确性。