日本宫颈癌患者中1型和2型疱疹病毒抗体
Antibodies to herpesvirus type 1 and type 2 among Japanese cervical cancer patients.
作者信息
Ozaki Y, Ishiguro T, Ohashi M, Sawaragi I, Ito Y
出版信息
Gan. 1978 Feb;69(1):119-22.
Antibodies to herpesvirus type 1 and type 2 were examined in 69 Japanese females with cancer of uterine cervix, which included cases of cervical dysplasia (7 cases), carcinoma in situ (9 cases), and invasive carcinoma (53 cases), and 112 matched controls. The presence of antibodies to type 2 virus was 42% in cervical dysplasia, 11% in carcinoma in situ, and 28% in invasive carcinoma, while such was 15% in matched controls. Mean antibody titer in log10 was 2.12 to type 1 and 1.65 to type 2 in women with invasive carcinoma, and 2.14 to type 1 and 1.67 to type 2 in the matched controls. The findings presented here did not support an association of type 2 virus infection with the occurrence of cervical cancer.
对69名患有子宫颈癌的日本女性（包括宫颈发育异常7例、原位癌9例和浸润癌53例）以及112名匹配对照者检测了1型和2型疱疹病毒抗体。2型病毒抗体的存在情况在宫颈发育异常中为42%，原位癌中为11%，浸润癌中为28%，而在匹配对照者中为15%。浸润癌女性中1型病毒的平均抗体滴度以log10计为2.12，2型为1.65；匹配对照者中1型为2.14，2型为1.67。此处呈现的研究结果不支持2型病毒感染与子宫颈癌发生之间存在关联。
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