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人类腹膜巨噬细胞对调理素化单核细胞增生李斯特菌的吞噬、杀伤及化学发光反应。

Human peritoneal macrophage phagocytic, killing, and chemiluminescent responses to opsonized Listeria monocytogenes.

作者信息

MacGowan A P, Peterson P K, Keane W, Quie P G

出版信息

Infect Immun. 1983 Apr;40(1):440-3. doi: 10.1128/iai.40.1.440-443.1983.

Abstract

Opsonization with normal human serum, purified immunoglobulin G, or immunoglobulin G-deficient serum promoted phagocytosis of Listeria monocytogenes by human peritoneal macrophages. However, normal human serum was the most effective opsonin in elicting killing and chemiluminescent responses. Macrophages phagocytized and killed almost as much as polymorphonuclear leukocytes but produced considerably less chemiluminescence.

摘要

用人正常血清、纯化的免疫球蛋白G或缺乏免疫球蛋白G的血清进行调理作用,可促进人腹膜巨噬细胞对单核细胞增生李斯特菌的吞噬作用。然而,人正常血清是引发杀伤和化学发光反应最有效的调理素。巨噬细胞吞噬和杀伤的细菌数量几乎与多形核白细胞相同,但产生的化学发光却少得多。

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