Möller P, Schüle B, Römmele U, Hüpen M
Virchows Arch A Pathol Anat Histopathol. 1983;399(2):245-53. doi: 10.1007/BF00619585.
We present a case of a 33 year old male with a history of early childhood diarrhoea and more recently diagnosed gluten sensitive enteropathy, who died with active disease, ulcerative proctosigmoiditis and desquamative erythrodermia associated with toxin induced shock. Autopsy revealed a tumour restricted to lymph nodes of the mesentery and the retroperitoneum. This is considered to be malignant histiocytosis of the intestine (MIH). Immunohistological examination of the diagnostic jejunal biopsy showed a pathological binding pattern for peanut lectin (PNL) within the enterocytes. This may be an expression of disturbed production or secretion of a product rich in non-reducing terminal D-galactosyl residues.
我们报告一例33岁男性病例，该患者有幼儿期腹泻病史，近期被诊断为麸质敏感性肠病，死于活动性疾病、溃疡性直肠乙状结肠炎及与毒素诱导性休克相关的剥脱性红皮病。尸检发现肿瘤局限于肠系膜和腹膜后淋巴结。这被认为是肠道恶性组织细胞增多症（MIH）。对诊断性空肠活检组织进行免疫组织学检查显示，肠细胞内花生凝集素（PNL）呈现病理结合模式。这可能是富含非还原性末端D - 半乳糖基残基的产物产生或分泌紊乱的一种表现。
