• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肠道恶性组织细胞增生症：早期组织学病变

Malignant histiocytosis of the intestine: the early histological lesion.

作者信息

Isaacson P

出版信息

Gut. 1980 May;21(5):381-6. doi: 10.1136/gut.21.5.381.

DOI:10.1136/gut.21.5.381
PMID:7429300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1419099/
Abstract

A histological study of peroral jejunal biopsies and resection specimens from patients with malignant histiocytosis of the intestine (MHI) has revealed characteristic lesions consisting of intramucosal histiocytic aggregations which invade surface and crypt epithelium. These lesions are found in 'uninvolved' jejunal mucosa in the presence of obvious tumour elsewhere and also in peroral jejunal biopsies many years earlier than the diagnosis of MHI. It is suggested that they represent the early lesion and their recognition in peroral jejunal biopsies could be important in improving the prognosis of the disease.

摘要

一项对肠道恶性组织细胞增多症（MHI）患者的经口空肠活检和切除标本的组织学研究显示，特征性病变由黏膜内组织细胞聚集构成，这些聚集侵犯表面和隐窝上皮。在其他部位存在明显肿瘤的情况下，这些病变可见于“未受累”的空肠黏膜，并且在经口空肠活检中出现的时间比MHI诊断早很多年。提示它们代表早期病变，在经口空肠活检中识别这些病变对于改善该疾病的预后可能很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/fc702b240b67/gut00438-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/5c68e399a0b6/gut00438-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/4fbb106f8b51/gut00438-0040-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/e1699a20b8c8/gut00438-0041-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/7001a38c8dba/gut00438-0041-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/a8530b1b1dc1/gut00438-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/dac3e4df5b32/gut00438-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/fc702b240b67/gut00438-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/5c68e399a0b6/gut00438-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/4fbb106f8b51/gut00438-0040-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/e1699a20b8c8/gut00438-0041-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/7001a38c8dba/gut00438-0041-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/a8530b1b1dc1/gut00438-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/dac3e4df5b32/gut00438-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/832e/1419099/fc702b240b67/gut00438-0043-a.jpg

相似文献

1
Malignant histiocytosis of the intestine: the early histological lesion.肠道恶性组织细胞增生症：早期组织学病变
Gut. 1980 May;21(5):381-6. doi: 10.1136/gut.21.5.381.
2
Ichthyosis and marrow involvement in malignant histiocytosis of the intestine.肠恶性组织细胞增多症中的鱼鳞病与骨髓受累
Br J Haematol. 1981 Jun;48(2):281-5.
3
Malignant histiocytosis of the intestine.
J Pathol. 1985 Nov;147(3):227-8. doi: 10.1002/path.1711470311.
4
Malignant histiocytosis (histiocytic medullary reticulosis) with spindle cell differentiation and tumour formation.伴有梭形细胞分化及肿瘤形成的恶性组织细胞增多症（组织细胞性髓性网状细胞增生症）
J Clin Pathol. 1977 Feb;30(2):120-5. doi: 10.1136/jcp.30.2.120.
5
Intestinal lymphoma associated with malabsorption.伴有吸收不良的肠道淋巴瘤。
Lancet. 1978 Jan 14;1(8055):67-70. doi: 10.1016/s0140-6736(78)90004-1.
6
Conspicuous enterocytic binding pattern for peanut lectin and malignant histiocytosis of the intestine.花生凝集素显著的肠上皮细胞结合模式与肠道恶性组织细胞增生症。
Virchows Arch A Pathol Anat Histopathol. 1983;399(2):245-53. doi: 10.1007/BF00619585.
7
Malignant histiocytosis of the intestine. Its relationship to malabsorption and ulcerative jejunitis.肠道恶性组织细胞增多症。其与吸收不良及空肠溃疡性病变的关系。
Hum Pathol. 1978 Nov;9(6):661-77. doi: 10.1016/s0046-8177(78)80049-5.
8
Villous atrophy with crypt hyperplasia in malignant histiocytosis of the nose.鼻部恶性组织细胞增多症中的绒毛萎缩伴隐窝增生
J Clin Pathol. 1982 Jun;35(6):606-10. doi: 10.1136/jcp.35.6.606.
9
Malignant histiocytosis of the intestine.
Dig Dis Sci. 1979 Aug;24(8):631-8. doi: 10.1007/BF01333708.
10
Clinical features and management of malignant histiocytosis of the intestine.肠道恶性组织细胞增多症的临床特征与治疗
Cancer. 1987 Dec 1;60(11):2791-6. doi: 10.1002/1097-0142(19871201)60:11<2791::aid-cncr2820601132>3.0.co;2-w.

引用本文的文献

1
[Acute abdomen in endemic sprue--a rare complication].[地方性口炎性腹泻中的急腹症——一种罕见的并发症]
Med Klin (Munich). 1998 Jan 15;93(1):43-6. doi: 10.1007/BF03045040.
2
Enteropathy associated T cell lymphoma presenting as an isolated CNS lymphoma three years after diagnosis of coeliac disease: T cell receptor polymerase chain reaction studies failed to show the original enteropathy to be a clonal disorder.乳糜泻诊断三年后出现的以孤立性中枢神经系统淋巴瘤为表现的肠病相关性T细胞淋巴瘤：T细胞受体聚合酶链反应研究未能显示原肠病为克隆性疾病。
Gut. 1997 Jun;40(6):801-3. doi: 10.1136/gut.40.6.801.
3
Early malignant histiocytosis of the intestine: an autopsy report.

本文引用的文献

1
Rectal biopsy as an aid to cancer control in ulcerative colitis.直肠活检辅助溃疡性结肠炎的癌症控制
Gut. 1967 Oct;8(5):423-34. doi: 10.1136/gut.8.5.423.
2
Steatorrhea and malignant lymphoma. The relationship of malignant tumors of lymphoid tissue and celiac disease.脂肪泻与恶性淋巴瘤。淋巴组织恶性肿瘤与乳糜泻的关系。
Am J Dig Dis. 1967 May;12(5):475-90. doi: 10.1007/BF02233180.
3
Malignant celiac syndrome. Report of two cases with malabsorption and microscopic foci of intestinal lymphoma.
肠道早期恶性组织细胞增多症：一份尸检报告。
Virchows Arch. 1994;424(3):327-30. doi: 10.1007/BF00194619.
4
Malignant histiocytosis of the intestine: report of three cases with immunological and cytochemical analysis.肠道恶性组织细胞增多症：三例报告及免疫和细胞化学分析
J Clin Pathol. 1982 May;35(5):510-6. doi: 10.1136/jcp.35.5.510.
5
Multiple and recurrent inflammatory fibroid polyps in three generations of a Devon family: a new syndrome.德文郡一个家族三代人中出现的多发性复发性炎性纤维瘤性息肉：一种新综合征。
Gut. 1984 Aug;25(8):854-62. doi: 10.1136/gut.25.8.854.
6
Malignancy in coeliac disease--effect of a gluten free diet.乳糜泻中的恶性肿瘤——无麸质饮食的影响。
Gut. 1989 Mar;30(3):333-8. doi: 10.1136/gut.30.3.333.
7
Coeliac disease and malignancy of the duodenum: diagnosis by endoscopy, successful treatment of the malignancy, and response to a gluten free diet.乳糜泻与十二指肠恶性肿瘤：通过内镜检查诊断、成功治疗恶性肿瘤以及对无麸质饮食的反应
Gut. 1991 Jan;32(1):90-2. doi: 10.1136/gut.32.1.90.
8
Peripheral T-cell lymphomas of the intestine.肠道外周T细胞淋巴瘤
Am J Pathol. 1992 Dec;141(6):1361-71.
Gastroenterology. 1970 Jul;59(1):130-9.
4
Coeliac disease, gluten-free diet, and malignancy.乳糜泻、无麸质饮食与恶性肿瘤
Gut. 1976 Aug;17(8):612-9. doi: 10.1136/gut.17.8.612.
5
Malignant histiocytosis of the intestine. Its relationship to malabsorption and ulcerative jejunitis.肠道恶性组织细胞增多症。其与吸收不良及空肠溃疡性病变的关系。
Hum Pathol. 1978 Nov;9(6):661-77. doi: 10.1016/s0046-8177(78)80049-5.
6
Malignant histiocytosis of the intestine.
Dig Dis Sci. 1979 Aug;24(8):631-8. doi: 10.1007/BF01333708.
7
The use of proteolytic enzymes to improve immunoglobulin staining by the PAP technique.使用蛋白水解酶通过过氧化物酶抗过氧化物酶技术改善免疫球蛋白染色。
Histochem J. 1979 May;11(3):345-57. doi: 10.1007/BF01005033.
8
Intestinal lymphoma associated with malabsorption.伴有吸收不良的肠道淋巴瘤。
Lancet. 1978 Jan 14;1(8055):67-70. doi: 10.1016/s0140-6736(78)90004-1.
9
Symposium on pathology of the gastrointestinal tract-Part II. Small intestinal biopsy.胃肠道病理学研讨会 - 第二部分。小肠活检。
Hum Pathol. 1975 Mar;6(2):157-217. doi: 10.1016/s0046-8177(75)80176-6.