Nance D M, White J P, Moger W H
Brain Res Bull. 1983 Mar;10(3):353-5. doi: 10.1016/0361-9230(83)90103-x.
The effects of hypothalamic hemi-islands on ovarian compensatory hypertrophy (OCH) were determined in prepubertal female rats. In animals with hypothalamic hemi-islands on the left side, OCH was blocked in rats hemi-ovariectomized on the ipsi- but not the contralateral side. A potential asymmetrical involvement of the hypothalamus in OCH was suggested by the further observation that this phenomenon could not be demonstrated in rats given hypothalamic hemi-islands on the right side and hemi-ovariectomized on the ipsi- or contralateral side. These data suggest that in addition to a possible direct neural contribution to endocrine feedback, the two-halves of the hypothalamus may differ in terms of their sensitivity to various components of endocrine control.
研究了下丘脑半岛对青春期前雌性大鼠卵巢代偿性肥大（OCH）的影响。在左侧有下丘脑半岛的动物中，同侧而非对侧进行半卵巢切除的大鼠的OCH被阻断。进一步观察发现，在右侧有下丘脑半岛且同侧或对侧进行半卵巢切除的大鼠中未出现这种现象，这表明下丘脑在OCH中可能存在潜在的不对称参与。这些数据表明，除了可能对内分泌反馈有直接神经贡献外，下丘脑的两半在对内分泌控制的各种成分的敏感性方面可能存在差异。
