Burden H W, Price G T, Davenport A T, Hodson C A
Department of Anatomy and Cell Biology, School of Medicine, East Carolina University, Greenville, NC 27858-4354.
Anat Embryol (Berl). 1993 May;187(5):461-4. doi: 10.1007/BF00174421.
Rats were subjected to right side dorsal rhizotomy of spinal nerves T12-L2 and ipsi- or contralateral unilateral ovariectomy at estrus (day 1). Estrous cycles were recorded daily, and on day 15 the remaining ovary was removed and weighed. Antral follicles were counted in representative day 1 and day 15 ovaries. Dorsal rhizotomy did not affect estrous cycles during the period after surgery. Also dorsal rhizotomy did not alter ipsilateral ovarian hypertrophy or follicular activation following unilateral ovariectomy. Thus, although the major portion of the ovarian sensory innervation is via the lesioned segments, interruption of these segments centrally does not alter compensatory ovarian responses subsequent to unilateral ovariectomy.
大鼠在动情期(第1天)接受T12-L2脊髓神经右侧背根切断术以及同侧或对侧单侧卵巢切除术。每天记录动情周期,在第15天切除并称重剩余卵巢。对第1天和第15天具有代表性的卵巢中的窦状卵泡进行计数。背根切断术在术后期间不影响动情周期。此外,背根切断术也不会改变单侧卵巢切除术后同侧卵巢肥大或卵泡激活情况。因此,尽管卵巢感觉神经支配的主要部分是通过受损节段,但在中枢中断这些节段并不会改变单侧卵巢切除术后的代偿性卵巢反应。