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背根切断术不会改变大鼠的发情周期或卵巢代偿反应。

Dorsal rhizotomy does not alter rat estrous cycles or ovarian compensatory responses.

作者信息

Burden H W, Price G T, Davenport A T, Hodson C A

机构信息

Department of Anatomy and Cell Biology, School of Medicine, East Carolina University, Greenville, NC 27858-4354.

出版信息

Anat Embryol (Berl). 1993 May;187(5):461-4. doi: 10.1007/BF00174421.

DOI:10.1007/BF00174421
PMID:8342791
Abstract

Rats were subjected to right side dorsal rhizotomy of spinal nerves T12-L2 and ipsi- or contralateral unilateral ovariectomy at estrus (day 1). Estrous cycles were recorded daily, and on day 15 the remaining ovary was removed and weighed. Antral follicles were counted in representative day 1 and day 15 ovaries. Dorsal rhizotomy did not affect estrous cycles during the period after surgery. Also dorsal rhizotomy did not alter ipsilateral ovarian hypertrophy or follicular activation following unilateral ovariectomy. Thus, although the major portion of the ovarian sensory innervation is via the lesioned segments, interruption of these segments centrally does not alter compensatory ovarian responses subsequent to unilateral ovariectomy.

摘要

大鼠在动情期(第1天)接受T12-L2脊髓神经右侧背根切断术以及同侧或对侧单侧卵巢切除术。每天记录动情周期,在第15天切除并称重剩余卵巢。对第1天和第15天具有代表性的卵巢中的窦状卵泡进行计数。背根切断术在术后期间不影响动情周期。此外,背根切断术也不会改变单侧卵巢切除术后同侧卵巢肥大或卵泡激活情况。因此,尽管卵巢感觉神经支配的主要部分是通过受损节段,但在中枢中断这些节段并不会改变单侧卵巢切除术后的代偿性卵巢反应。

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1
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本文引用的文献

1
The sensory innervation of the ovary: a horseradish peroxidase study in the rat.卵巢的感觉神经支配:大鼠辣根过氧化物酶研究
Anat Rec. 1983 Dec;207(4):623-7. doi: 10.1002/ar.1092070410.
2
Hypothalamic laterality in regulating gonadotropic function: unilateral hypothalamic lesion and ovarian compensatory hypertrophy.下丘脑在调节促性腺功能中的侧化作用:单侧下丘脑损伤与卵巢代偿性肥大。
Neurosci Lett. 1984 Oct 26;51(3):365-70. doi: 10.1016/0304-3940(84)90404-x.
3
Neural regulation of the ovary: evidence for hypothalamic asymmetry in endocrine control.
卵巢的神经调节:内分泌控制中下丘脑不对称性的证据。
Brain Res Bull. 1983 Mar;10(3):353-5. doi: 10.1016/0361-9230(83)90103-x.
4
Further evidence for hypothalamic asymmetry in endocrine control of the ovary.下丘脑在卵巢内分泌控制中的不对称性的进一步证据。
Brain Res Bull. 1984 Nov;13(5):651-5. doi: 10.1016/0361-9230(84)90197-7.
5
Influence of unilateral ovariectomy on follicular development in cycling rats.单侧卵巢切除对动情周期大鼠卵泡发育的影响。
Am J Anat. 1970 Jan;127(1):9-14. doi: 10.1002/aja.1001270103.
6
Effects of unilateral ovariectomy on follicular development and ovulation in cycling, aged rats.单侧卵巢切除术对性周期老化大鼠卵泡发育和排卵的影响。
Am J Anat. 1971 Dec;132(4):423-7. doi: 10.1002/aja.1001320403.
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A sex difference in the rat pituitary FSH response to unilateral gonadectomy as revealed in plasma radioimmunoassays.
Endocrinology. 1974 Feb;94(2):475-82. doi: 10.1210/endo-94-2-475.
8
The effects of vagotomy on compensatory ovarian hypertrophy and follicular activation after unilateral ovariectomy.迷走神经切断术对单侧卵巢切除术后代偿性卵巢肥大和卵泡激活的影响。
Anat Rec. 1986 Jan;214(1):61-6. doi: 10.1002/ar.1092140110.
9
Differences in the ovulation rate of the right or left ovary in unilaterally ovariectomized rats: effect of ipsi- and contralateral vagus nerves on the remaining ovary.单侧卵巢切除大鼠左右卵巢排卵率的差异:同侧和对侧迷走神经对剩余卵巢的影响。
J Endocrinol. 1987 Jun;113(3):397-401. doi: 10.1677/joe.0.1130397.
10
CGRP-immunoreactive nerves in the genitalia of the female rat originate from dorsal root ganglia T11-L3 and L6-S1: a combined immunocytochemical and retrograde tracing study.
Neurosci Lett. 1986 Aug 15;69(1):13-8. doi: 10.1016/0304-3940(86)90406-4.