柳氮磺胺吡啶用于预防大鼠腹膜粘连
Use of salazopyrin for prevention of peritoneal adhesions in rats.
作者信息
Golan J, Bercovici B, Dover N, Ben-Hur N
出版信息
Isr J Med Sci. 1976 Mar;12(3):257-9.
PMID:6406
Abstract
The effect of orally administered salazopyrin on the prevention of experimentally induced peritoneal adhesions in albino rats was investigated. Comparison of the findings with those for untreated rats and rats given penicillin for sulfadiazine indicated that salazopyrin has a preventive effect on the development of peritoneal adhesions. This effect is dose dependent and does not seem to be due merely to the antibacterial effect of the drug.
摘要
研究了口服柳氮磺胺吡啶对白化病大鼠实验性诱导腹膜粘连的预防作用。将研究结果与未治疗大鼠以及给予青霉素而非磺胺嘧啶的大鼠的结果进行比较，表明柳氮磺胺吡啶对腹膜粘连的发展具有预防作用。这种作用是剂量依赖性的，似乎不仅仅是由于药物的抗菌作用。
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