3,5,20-三乙酰大戟醇酯诱导腺瘤形成。
Adenoma formation by ingenol 3,5,20-triacetate.
作者信息
Tilabi J, Upadhyay R R
出版信息
Cancer Lett. 1983 Apr;18(3):317-20. doi: 10.1016/0304-3835(83)90242-2.
PMID:6406043
Abstract
Twice weekly i.p. administration of ingenol 3,5,20-triacetate in phosphate buffer saline (PBS), to a group of female NMRI mice, initiated topically with DMBA in acetone, developed no skin tumor, but produced high incidence of adenomas.
摘要
每周两次腹腔注射溶于磷酸盐缓冲盐水（PBS）的大戟醇3,5,20 - 三乙酸酯，对一组先用丙酮中的二甲基苯并蒽进行局部处理的雌性NMRI小鼠给药，未产生皮肤肿瘤，但腺瘤发病率很高。
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