Kaminski M V, Abrahamian V, Chrysomilides S A, Nasr N J, Armstrong M K, Lynch D M
JPEN J Parenter Enteral Nutr. 1983 Mar-Apr;7(2):126-30. doi: 10.1177/0148607183007002126.
The rate of fat emulsion clearance from the blood of 10 healthy adult male volunteers administered 0.1 gram of fat per kilogram body weight as 10% or 20% safflower oil emulsion (Liposyn) was studied. The subjects were hospitalized for 2 days and each was given the predetermined amount of one of the two fat emulsions (10% or 20%) by rapid injection into a peripheral vein and the rate of clearance of the emulsion determined over a 60-minute period, beginning when half of the emulsion had been injected. There was no significant difference in the clearance rate between the two emulsions. It is concluded that 20% fat emulsion is a safe as 10% fat emulsion for use in intravenous nutritional support.
对10名健康成年男性志愿者进行了研究，他们按每千克体重0.1克脂肪的剂量，静脉快速注射10%或20%的红花油乳剂（英脱利匹特），以此来研究脂肪乳剂从血液中清除的速率。受试者住院2天，每人通过外周静脉快速注射两种脂肪乳剂（10%或20%）中的一种预定剂量，并在注射一半乳剂时开始，在60分钟内测定乳剂的清除速率。两种乳剂的清除速率没有显著差异。得出的结论是，在静脉营养支持中，20%脂肪乳剂与10%脂肪乳剂一样安全。
