Dyckner T, Wester P O
Br Med J (Clin Res Ed). 1983 Jun 11;286(6381):1847-9. doi: 10.1136/bmj.286.6381.1847.
Twenty patients receiving long term diuretic treatment for arterial hypertension (18 patients) or congestive heart failure (two patients) received magnesium supplementation as aspartate hydrochloride 15 mmol/day for six months. Both systolic and diastolic pressures decreased significantly, by a mean of 12/8 mm Hg. No significant changes were recorded in plasma or urinary electrolytes except for magnesium, 24 hour urinary volumes, or body weight after treatment. The effect of magnesium on blood pressure may be direct or through influences on the internal balance of potassium, sodium, and calcium.
20例因动脉高血压(18例)或充血性心力衰竭(2例)接受长期利尿治疗的患者,接受了为期6个月的补充镁治疗,补充剂为盐酸天冬氨酸镁,剂量为15 mmol/天。收缩压和舒张压均显著降低,平均降低12/8 mmHg。治疗后,除镁、24小时尿量或体重外,血浆或尿电解质无显著变化。镁对血压的影响可能是直接的,也可能是通过影响钾、钠和钙的体内平衡。