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卵泡闭锁过程中促卵泡激素结合的放射自显影分析

Autoradiographic analysis of FSH binding during follicular atresia.

作者信息

Balachandran P K, Moodbidri S B, Nandedkar T D

出版信息

Experientia. 1983 Jul 15;39(7):792-3. doi: 10.1007/BF01990331.

Abstract

Binding of FSH to ovarian cells was studied in PMSG primed immature Swiss mice, 48 h after PMSG treatment, FSH-binding was higher in the periphery than in the cumulus cells of the antral follicles. Binding of FSH to granulosa cells of normal follicles was observed to be specific, 48 h after PMSG injection. No localization in the atretic follicles could be seen by autoradiography 72 h after priming.

摘要

在经孕马血清促性腺激素(PMSG)预处理的未成熟瑞士小鼠中研究了促卵泡激素(FSH)与卵巢细胞的结合情况。PMSG处理48小时后,FSH结合在窦状卵泡的周边细胞中高于卵丘细胞。在PMSG注射48小时后,观察到FSH与正常卵泡颗粒细胞的结合具有特异性。预处理72小时后,通过放射自显影未在闭锁卵泡中发现定位。

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