Claman H N
Hosp Pract (Off Ed). 1983 Jul;18(7):123-6, 131-4. doi: 10.1080/21548331.1983.11702591.
Although progress in understanding how steroids work has accelerated in the past few years, several important factors have eluded definitive analysis. Broadly, the mechanisms affect leukocyte traffic and function: Glucocorticoids inhibit the availability of leukocytes to the inflammatory site, interfere with their function at the site, and thus suppress the normal inflammatory response.
尽管在过去几年里,人们对类固醇作用机制的理解取得了快速进展,但仍有几个重要因素未能得到确切分析。总体而言,这些机制会影响白细胞的运输和功能:糖皮质激素会抑制白细胞到达炎症部位,干扰它们在炎症部位的功能,从而抑制正常的炎症反应。