促甲状腺激素释放激素与抑制素在雄性大鼠中的相互作用。
Interaction of thyrotrophin releasing hormone with inhibin in male rats.
作者信息
Sheth A R, Sheth P R, Roy R
出版信息
J Endocrinol. 1983 Jul;98(1):1-6. doi: 10.1677/joe.0.0980001.
PMID:6408216
Abstract
Inhibin administered to adult male rats delayed the in-vivo pituitary responsiveness to thyrotrophin releasing hormone (TRH) as observed in terms of prolactin release in the serum. It also decreased the sensitivity of the pituitary gland to TRH, in terms of TSH release. However, inhibin alone did not alter the serum levels of prolactin and TSH, although it significantly suppressed serum FSH levels. In addition, the inhibin effect on FSH release was blocked by TRH.
摘要
给成年雄性大鼠注射抑制素后，从血清中催乳素释放情况来看，其体内垂体对促甲状腺激素释放激素（TRH）的反应延迟。就促甲状腺激素（TSH）释放而言，它还降低了垂体对TRH的敏感性。然而，单独使用抑制素并不会改变血清中催乳素和TSH的水平，尽管它能显著抑制血清促卵泡生成素（FSH）水平。此外，TRH可阻断抑制素对FSH释放的作用。
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