Theuring F, Schultz M, Erbstösser E, von Bossányi P
Acta Histochem Suppl. 1983;27:211-7.
Tissue samples were obtained by operation on 23 patients with gastric and colonic carcinomas as well as gastric ulcers and polyps in the gastro-intestinal tract. The samples were taken from the pathological area and the "healthy" mucosa, respectively, 2 cm as the standardized distance from the respective place of finding. They were examined by means of in vitro-autoradiography with 3H-thymidine. The marking indiced obtained for benign, and malignant, tumours exceed distinctly the corrected labelled indiced of the normal mucous membrane. The marking values of the mucosa in the histologically inconspicuous vicinity of the carcinoma equal the carcinoma values. In correspondence to autoradiographic investigations by other authors and appropriate biopsy examinations in the neighbouring tumour regions, the in vitro-autoradiography is suggested to have some importance for the diagnosis of tumours.
对23例患有胃癌、结肠癌以及胃肠道胃溃疡和息肉的患者进行手术，获取组织样本。样本分别取自病理区域和“健康”黏膜，距各自发现部位的标准距离为2厘米。采用³H-胸腺嘧啶核苷进行体外放射自显影检查。良性和恶性肿瘤获得的标记指数明显超过正常黏膜的校正标记指数。癌组织在组织学上不明显的邻近区域黏膜的标记值与癌组织的值相等。与其他作者的放射自显影研究以及在邻近肿瘤区域进行的适当活检检查一致，建议体外放射自显影对肿瘤诊断具有一定重要性。
