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马来西亚士兵中恙虫病东方体抗体的产生情况

Development of antibody to Rickettsia tsutsugamushi in soldiers in Malaysia.

作者信息

Brown G W, Shirai A, Groves M G

出版信息

Trans R Soc Trop Med Hyg. 1983;77(2):225-7. doi: 10.1016/0035-9203(83)90079-2.

DOI:10.1016/0035-9203(83)90079-2
PMID:6408770
Abstract

Malaysian, British and New Zealand soldiers were tested for evidence of infection with Rickettsia tsutsugamushi after several weeks' exposure to the infection during field exercises in Malaysia. 39 (5.0%) of 787 British and New Zealand soldiers developed immunofluorescent antibody (IFA) to R. tsutsugamushi to a titre of 1:50 and two (0.3%) to a titre of 1:100. 11 (1.5%) of 751 Malaysian soldiers also developed low titres less than or equal to 1:100. These low antibody levels were not correlated with clinical disease, and their significance is unknown. Seven (0.9%) of the Malaysians showed an IFA rise to greater than or equal to 1:200, and three of these experienced febrile illnesses, one lasting two weeks. An additional eight Malaysian soldiers had an IFA titre of greater than or equal to 1:400 when first tested and six of these also had a Proteus OXK agglutinin titre of greater than or equal to 1:160, indicating infection shortly before the study.

摘要

在马来西亚进行野外演习期间,马来西亚、英国和新西兰士兵在接触感染源数周后,接受了恙虫病东方体感染证据检测。787名英国和新西兰士兵中,39人(5.0%)产生了针对恙虫病东方体的免疫荧光抗体(IFA),效价为1:50,2人(0.3%)效价为1:100。751名马来西亚士兵中,11人(1.5%)也产生了效价小于或等于1:100的低滴度抗体。这些低抗体水平与临床疾病无关,其意义尚不清楚。7名马来西亚人(0.9%)的IFA效价升至大于或等于1:200,其中3人出现发热性疾病,1人持续两周。另外8名马来西亚士兵首次检测时IFA效价大于或等于1:400,其中6人变形杆菌OXK凝集素效价也大于或等于1:160,表明在研究前不久感染。

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