Borisenko S A, Prokopenko P G, Makarov O V
Vopr Onkol. 1983;29(6):45-8.
Ferritin levels in extracts of tumor tissue and serum of patients with gynecological malignancies were assayed by immunodiffusion methods using a standard system of testing for ferritin. A high blood-ferritin level (500-1,000 ng/ml) was found in 8 out 21 patients with ovarian cancer, 8 out of 24 patients with endometrial carcinoma. 2 out of 8 cases of mucinous cystadenoma and in 2 out of 4 cases of pyoovarium. It was lower in other malignancies of the female genital tract. There was no correlation between the ferritin level of blood serum and that of tumor tissue extracts. Although blood serum ferritin was found in very few healthy subjects (2.5%), it is suggested that blood-ferritin level test should be carried out in the course of examination of slowly-progressing purulent adnexitis and mass screening for tumors of female genitals.
采用铁蛋白检测标准系统的免疫扩散法，对妇科恶性肿瘤患者的肿瘤组织提取物和血清中的铁蛋白水平进行了测定。在21例卵巢癌患者中有8例、24例子宫内膜癌患者中有8例、8例黏液性囊腺瘤中有2例以及4例卵巢积脓中有2例，发现血铁蛋白水平较高（500 - 1000 ng/ml）。在女性生殖道的其他恶性肿瘤中该水平较低。血清铁蛋白水平与肿瘤组织提取物的铁蛋白水平之间无相关性。虽然在极少数健康受试者（2.5%）中发现了血清铁蛋白，但建议在缓慢进展的化脓性附件炎检查过程中以及女性生殖器肿瘤的大规模筛查中进行血铁蛋白水平检测。
