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终末期肾病中老年患者的成功治疗。

Successful treatment of middle aged and elderly patients with end stage renal disease.

作者信息

Taube D H, Winder E A, Ogg C S, Bewick M, Cameron J S, Rudge C J, Williams D G

出版信息

Br Med J (Clin Res Ed). 1983 Jun 25;286(6383):2018-20. doi: 10.1136/bmj.286.6383.2018.

Abstract

Many patients over the age of 55 with end stage renal disease in the United Kingdom are denied dialysis or transplantation. Although the reasons are complex, anticipation of a poor prognosis for these patients might explain why most British renal units impose an arbitrary age limit on the acceptance of patients for treatment. A study was therefore conducted to examine the prognosis and quality of life of 84 patients (mean age 59.6 years, range 55-72) accepted into our renal replacement programme from the beginning of 1975. The five year survival of the patients was 62.0% with 78.1% of the survivors either having successful transplants or caring for themselves using home haemodialysis or continuous ambulatory peritoneal dialysis. The results show that in terms of survival, economics, and rehabilitation it is both feasible and reasonable to treat middle aged and elderly patients with end stage renal disease. These patients should therefore not be denied dialysis or transplantation on the basis of age alone, and the lack of resources and other factors that allow this state to persist in Britain should be rapidly redressed.

摘要

在英国,许多55岁以上的终末期肾病患者被拒绝接受透析或移植治疗。尽管原因很复杂,但预计这些患者预后不佳可能解释了为什么大多数英国肾脏科对接受治疗的患者设定了一个随意的年龄限制。因此,我们进行了一项研究,以调查自1975年初开始纳入我们肾脏替代治疗项目的84例患者(平均年龄59.6岁,范围55 - 72岁)的预后和生活质量。这些患者的五年生存率为62.0%,78.1%的幸存者要么成功接受了移植,要么通过家庭血液透析或持续性非卧床腹膜透析进行自我护理。结果表明,从生存、经济和康复方面来看,治疗中老年终末期肾病患者既可行又合理。因此,不应仅仅基于年龄而拒绝这些患者接受透析或移植治疗,而导致这种情况在英国持续存在的资源短缺及其他因素应迅速得到纠正。

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