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幼猪中MHC相容淋巴细胞的长期存活及同种异体不相容淋巴细胞的两阶段清除

Long-term survival of MHC-compatible lymphocytes and two-phase clearance of allogeneic incompatible lymphocytes in the young pig.

作者信息

Binns R M, Licence S T

出版信息

Immunology. 1983 Aug;49(4):727-30.

Abstract

Major histocompatibility complex (MHC)-compatible pig lymphocytes survive in vivo for well over a week. In the first day, they show a rapid reduction in numbers followed by reappearance in the blood consistent with equilibration with the lymphoreticular tissue populations, where they are found. By contrast, allogeneic lymphocytes show an early partial clearance and late (40-50 hr) exponential immune clearance.

摘要

主要组织相容性复合体(MHC)相容的猪淋巴细胞在体内存活超过一周。在第一天,它们的数量迅速减少,随后在血液中再次出现,这与它们在淋巴网状组织群体中达到平衡一致,它们正是在这些组织中被发现的。相比之下,同种异体淋巴细胞表现出早期部分清除和晚期(40 - 50小时)指数性免疫清除。

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