Effect of interferon on murine cytochrome P-450: effect of partially purified antigen-specific interferon-gamma.
作者信息
Smith P K, Nerland D E, Sonnenfeld G
出版信息
J Interferon Res. 1983;3(2):219-22. doi: 10.1089/jir.1983.3.219.
PMID:6409972
Abstract
Gamma interferon (IFN-gamma), induced by sensitization of mice with Mycobacterium bovis strain BCG followed by challenge with tuberculin, was partially purified by adsorption on silicic acid. Administration of the partially purified IFN-gamma to mice significantly depressed levels of liver microsomal cytochrome P-450 to an equivalent extent as crude IFN-gamma.
摘要
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