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早产儿肠外营养中的氨基酸。口服与肠外供给的比较。

Amino acids in parenteral nutrition of preterm infants. Comparison of oral and parenteral supply.

作者信息

Beganović N, Kok K, de Leeuw R, de Vries I J, Schutgens R

出版信息

Acta Paediatr Scand. 1983 May;72(3):421-5. doi: 10.1111/j.1651-2227.1983.tb09740.x.

DOI:10.1111/j.1651-2227.1983.tb09740.x
PMID:6410681
Abstract

Parenteral feeding of preterm infants has been accepted as an alternative form of nutrition in those infants unable to accept oral feeding. The amount of amino acid nitrogen and the composition of the amino acid solution to be used, however, have not yet been defined. The amino acid intake and the plasma amino acid concentration of three groups of preterm infants were compared. Twenty-three infants were fed parenterally. Of these, 16 were studied during the first week of life (group I) and 7 during the second week (group II). A control group of 9 infants fed with oral formula was also studied in the second week (group III). In general, plasma amino acid concentrations in the parenterally fed groups were higher than in the orally fed group, in spite of a lower intake. Comparison of the amino acid intake of groups I and II relative to group III, with the plasma amino acid concentrations of groups I and II relative to group III, revealed a rather constant ratio with the exception of tyrosine and aspartic acid, where higher values were found. It is concluded that further increase in the amino acid nitrogen in parenteral feeding of preterm infants requires a more adapted preparation.

摘要

对于无法接受经口喂养的早产儿,肠外营养已被视为一种替代营养方式。然而,所使用的氨基酸氮含量以及氨基酸溶液的组成尚未明确。比较了三组早产儿的氨基酸摄入量和血浆氨基酸浓度。23名婴儿接受肠外营养。其中,16名在出生第一周进行研究(第一组),7名在第二周进行研究(第二组)。第二周还研究了9名接受口服配方奶喂养的婴儿组成的对照组(第三组)。总体而言,尽管肠外营养组的摄入量较低,但其血浆氨基酸浓度高于经口喂养组。将第一组和第二组相对于第三组的氨基酸摄入量,与第一组和第二组相对于第三组的血浆氨基酸浓度进行比较,结果显示除酪氨酸和天冬氨酸外,比值相当恒定,而这两种氨基酸的值较高。得出的结论是,早产儿肠外营养中氨基酸氮的进一步增加需要更合适的制剂。

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1
Amino acids in parenteral nutrition of preterm infants. Comparison of oral and parenteral supply.早产儿肠外营养中的氨基酸。口服与肠外供给的比较。
Acta Paediatr Scand. 1983 May;72(3):421-5. doi: 10.1111/j.1651-2227.1983.tb09740.x.
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Plasma amino acids in supplementary parenteral nutrition of preterm infants. Effect of different quantities of amino acid infusion and comparison with enteral feeding.早产儿补充肠外营养时的血浆氨基酸。不同氨基酸输注量的影响及与肠内喂养的比较。
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Nutrients. 2024 Feb 1;16(3):440. doi: 10.3390/nu16030440.
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[Comparison of the metabolic response of the premature child fed parenterally, and then with mother's milk of prematurity].[经肠道外营养喂养的早产儿随后喂养早产母乳的代谢反应比较]
Can Med Assoc J. 1985 Feb 15;132(4):376-9.