Bergstrand G, Larsson S, Bergström M, Eriksson L, Edner G
AJNR Am J Neuroradiol. 1983 May-Jun;4(3):557-9.
Gamma camera cisternography after intrathecal administration of 111In-DTPA is a widely used and well established technique for studies of cerebrospinal fluid (CSF) circulation. The radiation dose from 111In, however, is a limiting factor that sometimes seriously affects the image quality and, hence, correct interpretation. This investigation was designed to assess the value of tomographic techniques for studies of CSF flow. Single-photon emission computed tomography (SPECT) was performed on 15 patients by means of the Karolinska Hospital rotating gamma camera system after injection of 111In-DTPA or 99mTc-DTPA. The combination of SPECT and 99mTc-DTPA proved to be a valuable technique. It permits a clear evaluation of the location of the isotope intracranially and its precise relation to the ventricles. Positron emission tomography (PET) applied after intrathecal administration of 68Ga-EDTA demonstrates that small amounts of radioactivity can be registered and that PET is a promising technique for the evaluation of CSF dynamics.
鞘内注射111In - DTPA后的γ相机脑池造影术是一种广泛应用且成熟的研究脑脊液（CSF）循环的技术。然而，来自111In的辐射剂量是一个限制因素，有时会严重影响图像质量，进而影响正确解读。本研究旨在评估断层扫描技术在CSF流动研究中的价值。在注射111In - DTPA或99mTc - DTPA后，通过卡罗林斯卡医院旋转γ相机系统对15例患者进行了单光子发射计算机断层扫描（SPECT）。SPECT与99mTc - DTPA的联合应用被证明是一种有价值的技术。它能够清晰地评估同位素在颅内的位置及其与脑室的确切关系。鞘内注射68Ga - EDTA后应用正电子发射断层扫描（PET）显示，可以记录到少量放射性，并且PET是评估CSF动力学的一种有前景的技术。
