通过单克隆抗体和免疫电子显微镜揭示的被膜小窝、细胞连接以及整个细胞表面的糖蛋白。
Glycoproteins of coated pits, cell junctions, and the entire cell surface revealed by monoclonal antibodies and immunoelectron microscopy.
作者信息
Murphy T L, Decker G, August J T
出版信息
J Cell Biol. 1983 Aug;97(2):533-41. doi: 10.1083/jcb.97.2.533.
Abstract
Topographical descriptions of three major plasma membrane glycoproteins of murine 3T3 cells were obtained by immunoelectron microscopy with monoclonal antibodies. A glycoprotein of Mr 80,000 was distributed throughout the total cell surface. A second of Mr 90,000 was concentrated in coated pits, and a third of Mr 100,000 was localized at cell junctions.
摘要
通过使用单克隆抗体的免疫电子显微镜技术，获得了小鼠3T3细胞三种主要质膜糖蛋白的拓扑学描述。一种分子量为80,000的糖蛋白分布在整个细胞表面。第二种分子量为90,000的糖蛋白集中在被膜小窝中，第三种分子量为100,000的糖蛋白定位在细胞连接处。
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