Miller L, Griffith J
Psychopharmacology (Berl). 1983;80(3):199-205. doi: 10.1007/BF00436152.
The subjective, behavioral, and physiological effects of bupropion, a nontricyclic antidepressant, were compared with those of dextroamphetamine and placebo in a randomized double-blind crossover study. The volunteers who participated were multiple-drug abusers. Six acute drug treatments, three doses of bupropion (100, 200, 400 mg), two doses of dextroamphetamine (15, 30 mg), and placebo were administered orally at intervals of not less than 72 h. Results indicated that the subjective effects of amphetamine as measured by the Addiction Research Center Inventory (ARCI) differed markedly from bupropion and placebo. Bupropion, in contrast to amphetamine, had no peripheral sympathomimetic effects and did not reduce appetite or caloric intake.
在一项随机双盲交叉研究中，将非三环类抗抑郁药安非他酮的主观、行为及生理效应与右旋苯丙胺和安慰剂进行了比较。参与研究的志愿者为多药滥用者。六种急性药物治疗，即三种剂量的安非他酮（100、200、400毫克）、两种剂量的右旋苯丙胺（15、30毫克）和安慰剂，每隔不少于72小时口服给药一次。结果表明，通过成瘾研究中心量表（ARCI）测得的苯丙胺主观效应与安非他酮和安慰剂明显不同。与苯丙胺不同，安非他酮没有外周拟交感神经效应，也不会降低食欲或热量摄入。
