口服铁剂与锌的生物利用度。
Oral iron and the bioavailability of zinc.
作者信息
Meadows N J, Grainger S L, Ruse W, Keeling P W, Thompson R P
出版信息
Br Med J (Clin Res Ed). 1983 Oct 8;287(6398):1013-4. doi: 10.1136/bmj.287.6398.1013.
Abstract
The oral bioavailability of zinc was studied in nonpregnant adults before and 24 hours after two weeks of oral supplementation with iron and folic acid. Bioavailability was greatly reduced, and the shape of the plasma curves suggested that this was due to impairment of the intestinal absorption of zinc. The findings suggest that the reduced bioavailability of zinc occurs because of interelement competition in the bowel wall. This might induce zinc depletion.
摘要
在非妊娠成年人中，研究了在口服铁和叶酸两周前后及两周后24小时锌的口服生物利用度。生物利用度大大降低，血浆曲线的形状表明这是由于锌的肠道吸收受损所致。研究结果表明，锌生物利用度降低是由于肠壁中元素间的竞争。这可能会导致锌缺乏。
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本文引用的文献
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