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[谷胱甘肽还原酶在“CK-MB抑制试验”中的干扰作用:抗谷胱甘肽还原酶消除谷胱甘肽还原酶的催化活性(作者译)]

[Interference by glutathione reductase in the "CK-MB-inhibition-test": elimination of the catalytic activity of glutathione reductase by anti-glutathione reductase (author's transl)].

作者信息

Weidemann G, Schmid R D

出版信息

J Clin Chem Clin Biochem. 1978 Apr;16(4):253-4.

PMID:641454
Abstract

Glutathione reductase interferes in the determiniation of creatine kinase-MB by the "CK-MB-inhibition-test". In 36 out of 55 serum samples with normal and elevated catalytic activities of creatine kinase, "negative" values greater than 14 U/l were obtained for the creatine kinase-MB. This interference by glutathione reductase is avoided by preincubation of the serum samples for 5 min with anti-glutathione reductase.

摘要

谷胱甘肽还原酶会干扰通过“CK-MB抑制试验”对肌酸激酶MB的测定。在55份肌酸激酶催化活性正常和升高的血清样本中,有36份样本的肌酸激酶MB得出了大于14 U/l的“阴性”值。血清样本与抗谷胱甘肽还原酶预孵育5分钟可避免谷胱甘肽还原酶的这种干扰。

相似文献

1
[Interference by glutathione reductase in the "CK-MB-inhibition-test": elimination of the catalytic activity of glutathione reductase by anti-glutathione reductase (author's transl)].[谷胱甘肽还原酶在“CK-MB抑制试验”中的干扰作用:抗谷胱甘肽还原酶消除谷胱甘肽还原酶的催化活性(作者译)]
J Clin Chem Clin Biochem. 1978 Apr;16(4):253-4.
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[Clinical significance of creatine kinase isoform assay by a new reagent based on immunoinhibition method].[基于免疫抑制法的新型试剂检测肌酸激酶同工酶的临床意义]
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Creatine kinase-MB activity: clinical and laboratory studies of specific immunochemical technique with optimized enzymatic assay.肌酸激酶-MB活性:采用优化酶法的特异性免疫化学技术的临床与实验室研究
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[Early diagnosis of myocardial infarct: value of the combined use of creatine kinase and MB isoenzyme determinations].[心肌梗死的早期诊断:肌酸激酶和MB同工酶联合检测的价值]
G Ital Cardiol. 1985 Feb;15(2):128-34.
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[Interference by glutathione reductase in the GSH-activated determinated of creatine kinase in serum (author's transl)].谷胱甘肽还原酶对血清中谷胱甘肽激活的肌酸激酶测定的干扰(作者译)
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Arch Intern Med. 1980 Mar;140(3):336-9.