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大肠杆菌SOS诱导后苯并芘加合物修复与诱变的时间差异。

Temporal distinction between repair and mutagenesis of benzopyrene adducts after SOS induction in Escherichia coli.

作者信息

Mizusawa H, Chakrabarti S, Seidman M

出版信息

J Bacteriol. 1983 Nov;156(2):926-30. doi: 10.1128/jb.156.2.926-930.1983.

DOI:10.1128/jb.156.2.926-930.1983
PMID:6415043
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217918/
Abstract

Plasmid DNA covalently modified with benzopyrene diol epoxide was introduced into Escherichia coli strains which differed in their capacity for repair and mutagenesis at various times after SOS induction. The uvrA+-dependent repair activity rose and fell before umuC+SOS-dependent mutagenesis was fully expressed.

摘要

将用苯并芘二醇环氧化物共价修饰的质粒DNA引入在SOS诱导后的不同时间其修复和诱变能力有所不同的大肠杆菌菌株中。uvrA⁺依赖性修复活性在umuC⁺SOS依赖性诱变充分表达之前先升高后下降。

相似文献

1
Temporal distinction between repair and mutagenesis of benzopyrene adducts after SOS induction in Escherichia coli.大肠杆菌SOS诱导后苯并芘加合物修复与诱变的时间差异。
J Bacteriol. 1983 Nov;156(2):926-30. doi: 10.1128/jb.156.2.926-930.1983.
2
Genetic factors in Escherichia coli that affect cell killing and mutagenesis induced by benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide.大肠杆菌中影响苯并(a)芘-7,8-二氢二醇9,10-环氧化物诱导的细胞杀伤和诱变的遗传因素。
Cancer Res. 1980 Oct;40(10):3508-11.
3
Stimulation of recombination between homologous sequences on carcinogen-treated plasmid DNA and chromosomal DNA by induction of the SOS response in Escherichia coli K12.通过诱导大肠杆菌K12中的SOS应答刺激致癌物处理的质粒DNA与染色体DNA上同源序列之间的重组。
Mol Gen Genet. 1985;201(1):129-32. doi: 10.1007/BF00397998.
4
Repair and mutagenesis of plasmid DNA modified by ultraviolet irradiation or N-acetoxy-N-2-acetylaminofluorene.紫外线照射或N-乙酰氧基-N-2-乙酰氨基芴修饰的质粒DNA的修复与诱变
Proc Natl Acad Sci U S A. 1982 Jul;79(13):4133-7. doi: 10.1073/pnas.79.13.4133.
5
Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.致癌物诱导的大肠杆菌野生型、uvrA和umuC菌株中的突变谱。菌株特异性和易突变序列。
J Mol Biol. 1984 Jul 25;177(1):33-51. doi: 10.1016/0022-2836(84)90056-1.
6
Post-replication repair and recombination in uvrA umuC strains of Escherichia coli are enhanced by vanillin, an antimutagenic compound.在大肠杆菌的uvrA umuC菌株中，复制后修复和重组会被香草醛（一种抗诱变化合物）增强。
Mutat Res. 1988 Sep;201(1):107-12. doi: 10.1016/0027-5107(88)90116-9.
7
Differences in transformation of repair-deficient mutants of E. coli with BPDE- or chlorozotocin-modified plasmid DNA.用BPDE或氯脲霉素修饰的质粒DNA对大肠杆菌修复缺陷型突变体进行转化时的差异。
Carcinogenesis. 1983 Nov;4(11):1379-84. doi: 10.1093/carcin/4.11.1379.
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Induction of SOS responses in Escherichia coli by 5-fluorouracil.
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Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101.大肠杆菌umuC突变体的诱变和修复缺陷被质粒pKM101抑制。
Mol Gen Genet. 1979 Apr 17;172(1):17-24. doi: 10.1007/BF00276210.
10
Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis.苯并[a]芘的(+)-反式二醇环氧化物在大肠杆菌质粒supF基因中的突变特异性：DNA序列背景影响热点、诱变特异性以及诱变SOS增强的程度。
Carcinogenesis. 1993 Mar;14(3):373-83. doi: 10.1093/carcin/14.3.373.

本文引用的文献

1
Repair and mutagenesis of plasmid DNA modified by ultraviolet irradiation or N-acetoxy-N-2-acetylaminofluorene.紫外线照射或N-乙酰氧基-N-2-乙酰氨基芴修饰的质粒DNA的修复与诱变
Proc Natl Acad Sci U S A. 1982 Jul;79(13):4133-7. doi: 10.1073/pnas.79.13.4133.
2
The SOS regulatory system of Escherichia coli.大肠杆菌的SOS调控系统。
Cell. 1982 May;29(1):11-22. doi: 10.1016/0092-8674(82)90085-x.
3
Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli.大肠杆菌中紫外线和化学诱变所需基因产物的可诱导性。
Proc Natl Acad Sci U S A. 1981 Sep;78(9):5749-53. doi: 10.1073/pnas.78.9.5749.
4
Mechanism of action of the lexA gene product.lexA基因产物的作用机制。
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4204-8. doi: 10.1073/pnas.78.7.4204.
5
An inducible DNA replication-cell division coupling mechanism in E. coli.大肠杆菌中的一种可诱导的DNA复制-细胞分裂偶联机制。
Nature. 1981 Apr 30;290(5809):797-9. doi: 10.1038/290797a0.
6
SOS induction and autoregulation of the himA gene for site-specific recombination in Escherichia coli.大肠杆菌中用于位点特异性重组的himA基因的SOS诱导及自动调节。
Proc Natl Acad Sci U S A. 1981 Nov;78(11):6754-8. doi: 10.1073/pnas.78.11.6754.
7
Expression of the E. coli uvrA gene is inducible.大肠杆菌uvrA基因的表达是可诱导的。
Nature. 1981 Feb 26;289(5800):808-10. doi: 10.1038/289808a0.
8
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.DNA损伤剂刺激大肠杆菌中特定基因座的基因表达。
Proc Natl Acad Sci U S A. 1980 May;77(5):2819-23. doi: 10.1073/pnas.77.5.2819.
9
Depurination causes mutations in SOS-induced cells.脱嘌呤作用会在SOS诱导的细胞中引发突变。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1773-7. doi: 10.1073/pnas.78.3.1773.
10
Alteration of plasmid DNA-mediated transformation and mutation induced by covalent binding of benzo[alpha]pyrene-7,8-dihydrodiol-9,10-oxide in Escherichia coli.苯并[a]芘-7,8-二氢二醇-9,10-环氧化物共价结合对大肠杆菌中质粒DNA介导的转化和突变的影响。
Mutat Res. 1981 Jun;82(1):47-57. doi: 10.1016/0027-5107(81)90137-8.