大肠杆菌SOS诱导后苯并芘加合物修复与诱变的时间差异。
Temporal distinction between repair and mutagenesis of benzopyrene adducts after SOS induction in Escherichia coli.
作者信息
Mizusawa H, Chakrabarti S, Seidman M
出版信息
J Bacteriol. 1983 Nov;156(2):926-30. doi: 10.1128/jb.156.2.926-930.1983.
Abstract
Plasmid DNA covalently modified with benzopyrene diol epoxide was introduced into Escherichia coli strains which differed in their capacity for repair and mutagenesis at various times after SOS induction. The uvrA+-dependent repair activity rose and fell before umuC+SOS-dependent mutagenesis was fully expressed.
摘要
将用苯并芘二醇环氧化物共价修饰的质粒DNA引入在SOS诱导后的不同时间其修复和诱变能力有所不同的大肠杆菌菌株中。uvrA⁺依赖性修复活性在umuC⁺SOS依赖性诱变充分表达之前先升高后下降。
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