Bolton R W
J Nutr. 1978 May;108(5):812-4. doi: 10.1093/jn/108.5.812.
A simple, inexpensive method for the rearing of germfree rats was developed. Germfree rats were fed from age 10 days to 40 weeks a diet consisting of commercially prepared Similac infant formula, water, and corn oil. Weight gains and gross appearances were comparable to littermate controls. Antibodies to bacterial teichoic acid were present in all controls while absent in rats fed the Similac diet.
开发了一种简单、低成本的无菌大鼠饲养方法。无菌大鼠从10日龄到40周龄喂食由市售的Similac婴儿配方奶粉、水和玉米油组成的饮食。体重增加和总体外观与同窝对照相当。所有对照中都存在针对细菌磷壁酸的抗体，而喂食Similac饮食的大鼠中则不存在。
