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红细胞和血浆输注对新生儿血清锌和铜水平的影响。

The effect of red cell and plasma transfusion on serum zinc and copper levels in the neonate.

作者信息

Lockitch G, Godolphin W J, Pendray M R, Quigley G

出版信息

Am J Clin Nutr. 1983 Nov;38(5):701-5. doi: 10.1093/ajcn/38.5.701.

DOI:10.1093/ajcn/38.5.701
PMID:6416047
Abstract

Transfusion of packed red cells (15 to 20 ml/kg) in 11 preterm infants resulted in a slight increase in mean serum zinc levels on the 3rd post transfusion day but no effect was noted on serum copper levels. No significant difference was found between the changes in serum zinc in 141 paired specimens collected a week apart when zero, one, two or three packed cell transfusions were given in the intervening week. A slight decrease in the mean copper level was noted when one transfusion was given. Transfusion of fresh frozen plasma in six newborns with abdominal wall defects resulted in initial serum copper levels two to three times greater than the reference mean for newborns. No effect was noted on zinc levels. Serum copper results should be interpreted with caution in infants who have been transfused with plasma.

摘要

对11名早产儿输注浓缩红细胞(15至20毫升/千克)后,输血后第3天血清锌平均水平略有升高,但血清铜水平未受影响。在相隔一周采集的141对样本中,若在其间一周内进行了零次、一次、两次或三次红细胞输注,血清锌变化无显著差异。进行一次输血时,血清铜平均水平略有下降。对6名患有腹壁缺陷的新生儿输注新鲜冰冻血浆后,初始血清铜水平比新生儿参考均值高两至三倍。锌水平未受影响。对于输注过血浆的婴儿,血清铜结果的解读应谨慎。

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