Kattan M, Keens T G, Mellis C M, Levison H
J Pediatr. 1978 May;92(5):718-21. doi: 10.1016/s0022-3476(78)80135-8.
Twenty-five normal and 105 asthmatic children were exercised on a treadmill. Pulmonary function was assessed before and after exercise. The maximum fall from the resting value in normal subjects depended on the test used: PEFR 12.5%; FEV1 10%; MMEF 26%; V50 30%; V25 33%. Using these criteria, PEFR and FEV1 detected 99% of those asthmatic children who had a positive exercise response. The largest fall from the resting value was seen with the MMEF, but this test detected only 70% of the positive responders. The pre-exercise function did not affect the severity of the response but did have an effect on the incidence of exercise-induced bronchospasm.
25名正常儿童和105名哮喘儿童在跑步机上进行运动。运动前后评估肺功能。正常受试者相对于静息值的最大降幅取决于所采用的测试：呼气峰流速（PEFR）为12.5%；第一秒用力呼气容积（FEV1）为10%；最大呼气中期流速（MMEF）为26%；50%肺活量时的呼气流量（V50）为30%；25%肺活量时的呼气流量（V25）为33%。根据这些标准，PEFR和FEV1检测出99%运动反应呈阳性的哮喘儿童。相对于静息值降幅最大的是MMEF，但该测试仅检测出70%的阳性反应者。运动前的肺功能不影响反应的严重程度，但确实对运动诱发支气管痉挛的发生率有影响。
