环氧丙烷和双醋酸氯己定溶液对用丙醇饱和的注射前拭子的杀菌能力。
The sterilizing capacity of propylene oxide and chlorhexidine diacetate solutions upon pre-injection swabs saturated with propan-2-ol.
作者信息
Wright R C
出版信息
J Hyg (Lond). 1983 Oct;91(2):287-92. doi: 10.1017/s0022172400060307.
The sporicidal activity of two solutions which have been used in the production of 'sterile' pre-injection swabs has been investigated. Propylene oxide (3.4% w/w) and chlorhexidine diacetate (0.6% w/w), both made up in approximately 65% w/w propan-2-ol, were artificially contaminated with spores of Bacillus subtilis var. niger and swabs were impregnated with these; surviving spores were enumerated at various temperatures and times of storage. Chlorhexidine diacetate had no sporicidal activity, whereas the activity of propylene oxide was dependent on temperature. The former should not be considered a sterilant and the latter can only be considered such if a controlled incubation period at an elevated temperature is employed.
对两种用于生产“无菌”注射前擦拭棒的溶液的杀孢子活性进行了研究。环氧丙烷（3.4% w/w）和双醋酸氯己定（0.6% w/w），均以约65% w/w的异丙醇配制，人工接种枯草芽孢杆菌黑色变种的孢子，然后用这些溶液浸渍擦拭棒；在不同温度和储存时间下对存活的孢子进行计数。双醋酸氯己定没有杀孢子活性，而环氧丙烷的活性取决于温度。前者不应被视为消毒剂，而后者只有在高温下采用受控孵育期时才可以被视为消毒剂。
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