Gismondo M R, Drago L, Lombardi A, Fassina M C, Mombelli B
Facoltà di Medicina e Chirurgia, Cattedra di Microbiologia Clinica, Università degli Studi, Milano.
Minerva Med. 1995 Jan-Feb;86(1-2):21-32.
The often indiscriminate use of antimicrobial agents has led to increased bacterial resistance over the past years. This phenomenon is above all evident in nosocomial environments but also at a community level. It is therefore important that, in addition to the rational use of antibiotics, an accurate prophylaxis is performed which includes the correct use of disinfectants. This study examines the antimicrobial activity of various commercially available disinfectant solutions consisting of one or more active ingredients. An analysis of the results reveals that products consisting of an association of individual components (quaternary ammonium chloride with o-phenylphenol and/or isopropyl alcohol; chlorhexidine with benzalkonium chloride or with diazolidinylurea and isopropanol) demonstrate a greater efficacy in terms of microbicidal concentration and contact times.
在过去几年中，抗菌剂的滥用导致细菌耐药性增加。这种现象首先在医院环境中尤为明显，但在社区层面也存在。因此，除了合理使用抗生素外，进行准确的预防措施很重要，这包括正确使用消毒剂。本研究考察了由一种或多种活性成分组成的各种市售消毒溶液的抗菌活性。结果分析表明，由单个成分组合而成的产品（季铵盐与邻苯基苯酚和/或异丙醇；洗必泰与苯扎氯铵或与重氮烷基脲和异丙醇）在杀菌浓度和接触时间方面表现出更高的效力。
