Walshaw M J, Pearson M G
Br Med J (Clin Res Ed). 1984 Jan 7;288(6410):15-7. doi: 10.1136/bmj.288.6410.15.
Sixteen patients with an early dense hemiplegia due to cerebrovascular accidents were shown to have a greater degree of hypoxia than 16 matched control patients. The patients with hemiplegia had a reflex compensatory fall in arterial carbon dioxide tensions (PaCO2) with possible reduction in cerebral blood flow. Oxygen treatment led to an increase in PaCO2 in the patients with hemiplegia, but the increase in oxygen tensions in these patients was significantly less than that in the control group, suggesting increased pulmonary shunting as the cause for the hypoxia. Oxygen treatment may improve cerebral blood flow and oxygenation and have a useful role in the early management of patients with a dense hemiplegia.
16例因脑血管意外导致早期严重偏瘫的患者,与16例匹配的对照患者相比,显示出更严重的缺氧程度。偏瘫患者动脉二氧化碳分压(PaCO2)出现反射性代偿性下降,脑血流量可能减少。氧疗导致偏瘫患者的PaCO2升高,但这些患者氧分压的升高明显低于对照组,提示肺内分流增加是缺氧的原因。氧疗可能改善脑血流量和氧合,在严重偏瘫患者的早期治疗中具有重要作用。