Lallemand R C, Vakil P A, Pearson P, Box V
Br Med J (Clin Res Ed). 1984 Jan 7;288(6410):31-3. doi: 10.1136/bmj.288.6410.31.
General practitioners screened 4284 asymptomatic people aged over 40 to compare the incidence of large bowel cancer and polyps with a control general practice (4288 patients). Compliance was best in young women (60%), and overall it was 42%. Twenty six patients who had a positive Haemoccult test result (1.5% of those screened) were examined by colonoscopy and 10 had polyps. The incidence of cancers in the two groups was similar but in the control (unscreened patients) practice no polyps were found.
全科医生对4284名40岁以上的无症状人群进行了筛查,以与一个对照全科诊所(4288名患者)比较大肠癌和息肉的发病率。年轻女性的依从性最佳(60%),总体依从性为42%。对26名潜血试验结果呈阳性的患者(占筛查者的1.5%)进行了结肠镜检查,其中10人有息肉。两组的癌症发病率相似,但在对照诊所(未筛查患者)未发现息肉。