Luo K X, Karayiannis P, Burns D M, Bamber M, Kernoff P, Thomas H
J Med Virol. 1983;12(4):253-65. doi: 10.1002/jmv.1890120405.
An antigen/antibody system associated with one form of parenterally transmitted non-A, non-B (NANB) hepatitis has been identified by solid-phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol-induced chronic liver disease, and primary biliary cirrhosis.
通过固相放射免疫测定法(RIA)已鉴定出一种与一种肠道外传播的非甲非乙型(NANB)肝炎相关的抗原/抗体系统。该抗原在3%的正常受试者中存在,在血友病患者、肾移植受者、同性恋男性、妓女、吸毒者以及慢性乙型肝炎病毒(HBV)感染患者中的出现频率增加。在甲型和乙型急性肝炎、散发性NANB肝炎(非吸毒者)、自身免疫性和酒精性慢性肝病以及原发性胆汁性肝硬化患者中,该抗原的出现频率正常。