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通过放射免疫测定法在急慢性肝病中检测到的非甲非乙型相关抗原/抗体系统的患病率。

Prevalence of a non-A, non-B-associated antigen/antibody system detected by radioimmunoassay in acute and chronic liver disease.

作者信息

Luo K X, Karayiannis P, Burns D M, Bamber M, Kernoff P, Thomas H

出版信息

J Med Virol. 1983;12(4):253-65. doi: 10.1002/jmv.1890120405.

DOI:10.1002/jmv.1890120405
PMID:6418856
Abstract

An antigen/antibody system associated with one form of parenterally transmitted non-A, non-B (NANB) hepatitis has been identified by solid-phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol-induced chronic liver disease, and primary biliary cirrhosis.

摘要

通过固相放射免疫测定法(RIA)已鉴定出一种与一种肠道外传播的非甲非乙型(NANB)肝炎相关的抗原/抗体系统。该抗原在3%的正常受试者中存在,在血友病患者、肾移植受者、同性恋男性、妓女、吸毒者以及慢性乙型肝炎病毒(HBV)感染患者中的出现频率增加。在甲型和乙型急性肝炎、散发性NANB肝炎(非吸毒者)、自身免疫性和酒精性慢性肝病以及原发性胆汁性肝硬化患者中,该抗原的出现频率正常。

相似文献

1
Prevalence of a non-A, non-B-associated antigen/antibody system detected by radioimmunoassay in acute and chronic liver disease.通过放射免疫测定法在急慢性肝病中检测到的非甲非乙型相关抗原/抗体系统的患病率。
J Med Virol. 1983;12(4):253-65. doi: 10.1002/jmv.1890120405.
2
Detection of an antigen-antibody system in serum associated with human non-A, non-B hepatitis.血清中与人类非甲非乙型肝炎相关的抗原-抗体系统的检测。
J Med Virol. 1979;4(3):161-9. doi: 10.1002/jmv.1890040302.
3
Evaluation of the specificity of an immunoprecipitin test for non-A, non-B hepatitis.非甲非乙型肝炎免疫沉淀试验特异性的评估。
J Infect Dis. 1983 Apr;147(4):702-10. doi: 10.1093/infdis/147.4.702.
4
Detection by immunofluorescence of an antigen-antibody system in patients with acute and chronic non-A, non-B hepatitis.用免疫荧光法检测急慢性非甲非乙型肝炎患者抗原抗体系统。
Liver. 1981 Sep;1(3):183-90. doi: 10.1111/j.1600-0676.1981.tb00032.x.
5
[The clinical behaviour of by immunology unique courses of NANB hepatitis (author's transl)].[非甲非乙型肝炎免疫学独特病程的临床行为(作者译)]
Z Gastroenterol. 1982 May;20(5):278-85.
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Detection of virus-associated antigen in serum and liver of patients with non-A non-B hepatitis.非甲非乙型肝炎患者血清及肝脏中病毒相关抗原的检测
Lancet. 1979 Dec 15;2(8155):1263-7. doi: 10.1016/s0140-6736(79)92280-3.
7
Detection by immunofluorescence of a new "core-like" Ag/Ab system in liver and serum of patients with NANB hepatitis.用免疫荧光法检测非甲非乙型肝炎患者肝脏和血清中一种新的“核心样”抗原/抗体系统。
Liver. 1981 Sep;1(3):191-200. doi: 10.1111/j.1600-0676.1981.tb00033.x.
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[Non-A, non-B hepatitis virus related to antigens and antibodies].[与抗原和抗体相关的非甲非乙型肝炎病毒]
Nihon Rinsho. 1981 Oct;39(10):3174-81.
9
Post-transfusion hepatitis: antigen/antibody systems correlated with non-A, non-B hepatitis.输血后肝炎:与非甲非乙型肝炎相关的抗原/抗体系统
J Med Virol. 1980;6(2):147-51. doi: 10.1002/jmv.1890060207.
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An enzyme-linked immunoassay for the possible detection of non-A, non-B viral antigen in patients with epidemic viral hepatitis.一种用于检测流行性病毒性肝炎患者中可能存在的非甲非乙型病毒抗原的酶联免疫测定法。
Liver. 1988 Apr;8(2):111-5. doi: 10.1111/j.1600-0676.1988.tb00977.x.

引用本文的文献

1
Acute fulminant non-A, non-B hepatitis leading to chronic active hepatitis after treatment with cryoprecipitate.经冷沉淀治疗后发生急性暴发性非甲非乙型肝炎并导致慢性活动性肝炎。
Gut. 1985 Jun;26(6):639-41. doi: 10.1136/gut.26.6.639.