Das R M, Martin L
J Reprod Fertil. 1978 May;53(1):125-8. doi: 10.1530/jrf.0.0530125.
[3H]Thymidine autoradiography was used to study cell proliferation during decidualization induced by intraluminal oil in ovariectomized mice treated with oestrogen and progesterone. Development of the decidual reaction involves two distinct populations of stromal cells. Periluminal cells start to synthesize DNA 11--15 h after instillation and by 17--20 h, without dividing, differentiate into epithelioid decidual cells which continue to incorporate [3H]thymidine, presumably becoming polyploid. Cells peripheral to this zone also start to synthesize DNA between 11 and 15 h, but at 18.5 h many have divided before differentiating. None of these dividing cells had been arrested in G2. The periluminal and peripheral cells do not appear to differ in their proliferative antecedents.
采用[3H]胸腺嘧啶核苷放射自显影术，研究雌激素和孕激素处理的去卵巢小鼠经腔内注射油诱导蜕膜化过程中的细胞增殖情况。蜕膜反应的发展涉及两种不同类型的基质细胞。腔周细胞在滴注后11 - 15小时开始合成DNA，到17 - 20小时，不经过分裂，分化为上皮样蜕膜细胞，这些细胞继续掺入[3H]胸腺嘧啶核苷，推测会变成多倍体。该区域外周的细胞也在11至15小时之间开始合成DNA，但在18.5小时时，许多细胞在分化之前已经分裂。这些分裂的细胞均未在G2期停滞。腔周细胞和外周细胞在增殖前体方面似乎没有差异。
