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膝关节兆伏级放疗的胎儿剂量评估及新生儿随访

Evaluation of fetal dose from megavoltage irradiation of the knee and neonate followup.

作者信息

Nair R P, Nair T K, El-Akkad S

出版信息

Med Phys. 1983 Nov-Dec;10(6):862-5. doi: 10.1118/1.595349.

DOI:10.1118/1.595349
PMID:6419033
Abstract

A 24-yr-old female patient who was to undergo radiation therapy management for a recurrent low-grade fibrosarcoma on her right knee was found to be 9 weeks pregnant. The patient and her relatives insisted on carrying the pregnancy to maturity, despite undergoing irradiation of her right knee for local control of her disease and to take the teratological risk, if any, that it entails. This paper discusses the measurement of scattered dose in water, fetal dose estimation in an Alderson-Rando human phantom and possible ways of minimizing it.

摘要

一名24岁的女性患者,因右膝复发性低度纤维肉瘤需接受放射治疗,却被发现已怀孕9周。尽管为控制病情需对其右膝进行照射,并承担由此带来的致畸风险(如有),但患者及其亲属仍坚持要将妊娠维持至足月。本文讨论了水中散射剂量的测量、在Alderson-Rando人体模型中对胎儿剂量的估计以及将其降至最低的可能方法。

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Evaluation of fetal dose from megavoltage irradiation of the knee and neonate followup.膝关节兆伏级放疗的胎儿剂量评估及新生儿随访
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引用本文的文献

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Comparative analysis of fetal dose sparing between a C-arm linac and an O-ring linac in a SIB-VMAT sarcoma treatment for a pregnant patient: A technical note and case report.C型臂直线加速器与O型环直线加速器在一名孕妇肉瘤患者的同步整合加量容积调强放疗中胎儿剂量保护的对比分析:技术说明与病例报告
J Appl Clin Med Phys. 2025 Jan;26(1):e14556. doi: 10.1002/acm2.14556. Epub 2024 Nov 4.
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A study of the shielding used to reduce leakage and scattered radiation to the fetus in a pregnant patient treated with a 6-MV external X-ray beam.一项关于在接受6兆伏外部X射线束治疗的孕妇中用于减少胎儿泄漏和散射辐射的屏蔽的研究。
Health Phys. 2009 Dec;97(6):581-9. doi: 10.1097/01.HP.0000363838.70546.4c.
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A feasibility study to calculate unshielded fetal doses to pregnant patients in 6-MV photon treatments using Monte Carlo methods and anatomically realistic phantoms.
一项使用蒙特卡罗方法和解剖学逼真体模计算6兆伏光子治疗中孕妇患者未屏蔽胎儿剂量的可行性研究。
Med Phys. 2008 Jul;35(7):3054-61. doi: 10.1118/1.2938519.
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Fetal outcome after maternal radiation treatment of supradiaphragmatic Hodgkin's disease.母亲接受膈上霍奇金淋巴瘤放射治疗后的胎儿结局。
CMAJ. 1993 Nov 1;149(9):1281-3.